The Bills lost 23-20 in their showdown with the Texans in Houston on October 6, 2024. Now, they will face off again at NRG Stadium in Week 12 for Thursday Night Football.
Key Takeaways:
The Bills will play the Texans on Thursday, November 20th, 2025, in a Week 12 showdown at NRG Stadium.
The Bills are currently favored to win this game by 3.5 points, a very close line, considering they are both divisional champions.
Bills vs. Texans Odds: Who Is Favored To Win?
The Bills are currently favored by 3.5 points to beat the Texans in Week 12, meaning they must beat Houston by at least four points to cover the spread.
Team
Bills
Texans
Spread
-3.5 (-110)
+3.5 (-110)
Total
O 46.5 (-110)
46.5 (-110)
Moneyline
-175
+145
What The Spread Tells Us
The spread tells us that the Bills are predicted to win and cover the spread on the road. Notably, oddsmakers are giving the Bills 3.5 points, which suggests that this game could come down to the wire.
What The Moneyline Tells Us
Despite the game being in Houston, and the Texans beating the Bills last season at NRG Stadium, the Bills have the edge. If you were to bet on the Texans to win this game, you would get a higher payout due to the Bills being the favorites.
How The Bills Beat The Texans
The Bills need a better performance across the board from Josh Allen after he went 9 for 30 with 131 yards passing and a touchdown pass while rushing four times for 54 yards. James Cook must replicate his performance, after he ran 20 times for 82 yards and a touchdown. The Bills must improve on third down, having converted just 3 of 14 attempts against the Texans last season. The defense was on the field too long last time, and must contain CJ Stroud.
How The Texans Beat the Bills
The Texans controlled the clock in their 23-20 win against the Bills last season. Because of this, they were able to keep Allen off the field. Stroud did well, going 28 for 38 with 331 yards and a touchdown pass and an interception while rushing three times for 27 yards. Nico Collins had two catches for 78 yards and a touchdown. The defense must continue to tighten up and not allow Allen to make any plays.
Line: The Bills are favorites against the Texans in Week 12 of the NFL season.
History of Bills vs. Texans
The Bills and Texans have played 12 games in their history, including one playoff game. Recently, the games in Houston have been close, as evidenced by the game last season. Josh Allen is 1-2 against the Texans, as they are one of the few teams against which he has a losing record.
All-Time Best Bills vs. Texans Games
The Bills and Texans have played in some memorable games. There are a few options to consider, even within the handful of games, and we will select the best three to choose from. All three of the best games happened in Houston.
1. Bills vs. Texans, AFC Wildcard Game - January 1, 2020
The first game on this list is the only playoff game the teams have played against one another. And it was a thrilling showdown that started with the Bills jumping out to a 16-0 lead. Then, the Texans slowly crawled back and briefly had the lead in the fourth quarter before Stephen Hauschka tied it to force overtime. Deshaun Watson led an incredible drive to set up the game-winning field goal in overtime.
2. Bills vs. Texans - October 6, 2024
The Bills went into this game as the favorites and struggled mightily from the outset, trailing 14-3 after the first quarter. It was 20-3 in the third quarter when Josh Allen led a comeback attempt that started with a touchdown run from James Cook and a touchdown reception from Keon Coleman. After tying the game, the Bills could not stop the drive by Stroud, who set up Ka'imi Fairbairn for the game-winning field goal.
3. Bills vs. Texans -November 19, 2006
J.P. Losman connected with Lee Evans on two touchdowns to give the Bills the early lead. Then, after allowing the Texans to score three touchdowns and take a lead, the Bills won the game thanks to a touchdown pass from Losman to Peerless Price with nine seconds left to steal the victory. Evans set a Bills' record for receiving yards in one game with an astounding 265 yards.
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The Bills will face the Texans in Week 12 on Sunday, November 20, 2025, at NRG Stadium in Houston, Texas. It will be a Thursday Night Football showdown in primetime as two divisional leaders clash, with potential playoff scenarios starting to take shape.
The Bills defeated the Texans 31-24 in the first game between the teams on October 13, 2002, at Reliant Stadium. Drew Bledsoe led the Bills with 254 yards passing while hurling two touchdowns, and Travis Henry ran all over the Texans, running 28 times for 159 yards and two scores.
The Texans lead the all-time series 7-5, as the teams have played a total of 12 games. Notably, the Texans are 1-0 against the Bills in the playoffs, having defeated them in the 2020 AFC Wild Card Game.
The Bills are currently favored to beat the Texans, with a spread of -3.5 points. The lines may shift as the game gets closer, but oddsmakers seem to believe the Bills will win this game by at least one score.
You can place a bet on the Bills-Texans game in Week 12 by utilizing any of the licensed sportsbooks in Ontario. Some solid options to choose from include betMGM, FanDuel, Caesars Sportsbook, DraftKings Sportsbook, and PointsBet Canada Sportsbook.
Brandon Justice has nearly a decade of experience covering sports and betting, primarily working in college football, college basketball, NFL and MLB. His goal is providing detailed analysis on the trends & data of sports betting with a wealth of experience, including writing for The Action Network & Rivals.com.