The Bills lost 23-19 in their showdown with the Texans in Houston on November 21, 2025. Now, the Texans have won two in a row against the Bills, and there is a chance they will meet in the playoffs
Key Takeaways:
The Texans defeated the Bills 23-19 in Week 12
There are no additional games scheduled for the 2025 season, but there is still the chance they meet in the playoffs. This could happen if the Texans win the AFC South, or if the Texans finish as a wild card and the Bills win the division while lining up against them.
Bills vs. Texans Odds: Who Is Favored To Win?
The Bills were favored to win, but the Texans won in Week 12.
Team
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What The Spread Tells Us
The Bills lost, so they failed to cover the spread against the Texans.
What The Moneyline Tells Us
The Bills had the edge, but the Texans won the game. How they do the rest of the season will dictate who is the favorite in the next game they face.
How The Bills Beat The Texans
The Bills need a better performance across the board from Josh Allen after he went 9 for 30 with 131 yards passing and a touchdown pass while rushing four times for 54 yards. James Cook must replicate his performance, after he ran 20 times for 82 yards and a touchdown. The Bills must improve on third down, having converted just 3 of 14 attempts against the Texans last season. The defense was on the field too long last time, and must contain CJ Stroud this time.
How The Texans Beat the Bills
The Texans controlled the clock in their 23-20 win against the Bills last season. Because of this, they were able to keep Allen off the field. Stroud did well, going 28 for 38 with 331 yards and a touchdown pass and an interception while rushing three times for 27 yards. Nico Collins had two catches for 78 yards and a touchdown. The defense must continue to tighten up and not allow Allen to make any plays.
Line: The Bills are the favorites against the Texans in Week 13 of the NFL season.
History of Bills vs. Texans
The Bills and Texans have played 13 games in their history, including one playoff game. Recently, the games in Houston have been close, as evidenced by the game last season. Josh Allen is 1-3 against the Texans, as they are one of the few teams against which he has a losing record.
All-Time Best Bills vs. Texans Games
The Bills and Texans have played in some memorable games. There are a few options to consider, even within the handful of games, and we will select the best three to choose from. All three of the best games happened in Houston.
1. Bills vs. Texans, AFC Wildcard Game - January 1, 2020
The first game on this list is the only playoff game the teams have played against one another. And it was a thrilling showdown that started with the Bills jumping out to a 16-0 lead. Then, the Texans slowly crawled back and briefly had the lead in the fourth quarter before Stephen Hauschka tied it to force overtime. Deshaun Watson led an incredible drive to set up the game-winning field goal in overtime.
2. Bills vs. Texans - October 6, 2024
The Bills went into this game as the favorites and struggled mightily from the outset, trailing 14-3 after the first quarter. It was 20-3 in the third quarter when Josh Allen led a comeback attempt that started with a touchdown run from James Cook and a touchdown reception from Keon Coleman. After tying the game, the Bills could not stop the drive by Stroud, who set up Ka'imi Fairbairn for the game-winning field goal.
3. Bills vs. Texans -November 19, 2006
J.P. Losman connected with Lee Evans on two touchdowns to give the Bills the early lead. Then, after allowing the Texans to score three touchdowns and take a lead, the Bills won the game thanks to a touchdown pass from Losman to Peerless Price with nine seconds left to steal the victory. Evans set a Bills record for receiving yards in one game with an astounding 265 yards.
After their Week 12 clash, there are no scheduled games left for the season. But the Texans still have a chance to meet the Bills in the playoffs if they can make it and if the Bills can also make it. Currently, both teams have a chance.
The Bills defeated the Texans 31-24 in the first game between the teams on October 13, 2002, at Reliant Stadium. Drew Bledsoe led the Bills with 254 yards passing while hurling two touchdowns, and Travis Henry ran all over the Texans, running 28 times for 159 yards and two scores.
The Texans lead the all-time series 8-5, as the teams have played a total of 13 games. Notably, the Texans are 1-0 against the Bills in the playoffs, having defeated them in the 2020 AFC Wild Card Game.
The Bills were favored to beat the Texans, with a spread of -5.5 points. Despite this, the Texans were able to overcome the odds and beat the Bills 23-19, their second straight win over the Bills in a one-year span.
You can place a bet on the Bills-Texans game in Week 12 by utilizing any of the licensed sportsbooks in Ontario. Some solid options to choose from include betMGM, FanDuel, Caesars Sportsbook, DraftKings Sportsbook, and PointsBet Canada Sportsbook.
Brandon Justice has nearly a decade of experience covering sports and betting, primarily working in college football, college basketball, NFL and MLB. His goal is providing detailed analysis on the trends & data of sports betting with a wealth of experience, including writing for The Action Network & Rivals.com.